November 15, 2024 Michael W. Kalb EVP and Chief Financial Officer CATALYST PHARMACEUTICALS, INC. 355 Alhambra Circle Suite 801 Coral Gables, FL 33134 Re: CATALYST PHARMACEUTICALS, INC. Form 10-Q for the period ending June 30, 2024 Filed August 7, 2024 Form 8-K filed February 29, 2024 File No. 001-33057 Dear Michael W. Kalb: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences